KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F5
All Species:
25.76
Human Site:
S54
Identified Species:
40.48
UniProt:
Q15329
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15329
NP_001077057.1
346
37610
S54
G
S
S
R
H
E
K
S
L
G
L
L
T
T
K
Chimpanzee
Pan troglodytes
XP_511025
426
45548
S40
T
P
S
R
H
E
K
S
L
G
L
L
T
T
K
Rhesus Macaque
Macaca mulatta
XP_001094919
346
37697
S54
G
S
S
R
H
E
K
S
L
G
L
L
T
T
K
Dog
Lupus familis
XP_853833
304
33793
N30
G
L
G
S
H
A
V
N
L
I
I
N
L
F
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61502
335
36766
S44
G
S
S
R
H
E
K
S
L
G
L
L
T
T
K
Rat
Rattus norvegicus
Q62814
300
33206
D30
E
A
Q
D
G
V
L
D
L
K
A
A
A
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517985
227
25092
Chicken
Gallus gallus
Q90977
403
43534
S108
E
K
S
R
Y
E
T
S
L
N
L
T
T
K
R
Frog
Xenopus laevis
NP_001086706
375
40890
Q30
S
K
F
V
S
L
L
Q
E
A
E
D
G
V
L
Zebra Danio
Brachydanio rerio
NP_998597
393
42365
A31
F
V
T
L
L
Q
E
A
K
D
G
V
L
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q27368
805
87442
S258
D
R
N
R
A
D
T
S
L
G
I
L
T
K
K
Honey Bee
Apis mellifera
XP_624285
300
34327
G30
L
L
Q
K
A
K
D
G
V
L
D
L
K
V
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799123
356
39484
R51
L
A
V
R
Q
K
R
R
I
Y
D
I
T
N
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130952
446
48668
S134
G
G
C
R
Y
D
S
S
L
G
L
L
T
K
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_565831
483
52579
S171
G
S
C
R
Y
D
S
S
L
G
L
L
T
K
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.8
97.9
78.9
N.A.
88.1
82.6
N.A.
57.2
33
58.1
56.2
N.A.
20.6
41
N.A.
51.9
Protein Similarity:
100
62.2
98.5
82.6
N.A.
90.1
84.3
N.A.
60.6
49.6
68.8
66.1
N.A.
29.6
55.2
N.A.
65.1
P-Site Identity:
100
86.6
100
20
N.A.
100
6.6
N.A.
0
46.6
0
0
N.A.
46.6
6.6
N.A.
13.3
P-Site Similarity:
100
86.6
100
33.3
N.A.
100
13.3
N.A.
0
60
0
33.3
N.A.
66.6
26.6
N.A.
46.6
Percent
Protein Identity:
N.A.
31.3
N.A.
28.1
N.A.
N.A.
Protein Similarity:
N.A.
45
N.A.
41.2
N.A.
N.A.
P-Site Identity:
N.A.
60
N.A.
66.6
N.A.
N.A.
P-Site Similarity:
N.A.
73.3
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
14
0
0
14
7
0
7
0
7
7
7
7
0
7
% A
% Cys:
0
0
14
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
0
7
0
20
7
7
0
7
14
7
0
14
0
% D
% Glu:
14
0
0
0
0
34
7
0
7
0
7
0
0
0
0
% E
% Phe:
7
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
40
7
7
0
7
0
0
7
0
47
7
0
7
0
0
% G
% His:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
7
7
14
7
0
0
0
% I
% Lys:
0
14
0
7
0
14
27
0
7
7
0
0
7
27
47
% K
% Leu:
14
14
0
7
7
7
14
0
67
7
47
54
14
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
7
0
7
0
7
0
7
0
% N
% Pro:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
14
0
7
7
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
60
0
0
7
7
0
0
0
0
0
0
7
% R
% Ser:
7
27
34
7
7
0
14
54
0
0
0
0
0
0
0
% S
% Thr:
7
0
7
0
0
0
14
0
0
0
0
7
60
27
7
% T
% Val:
0
7
7
7
0
7
7
0
7
0
0
7
0
14
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
20
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _